Covid-19 e suas repercussões no sistema nervoso: uma revisão narrativa da literatura
Resumo
Introdução: A COVID-19, causada pelo vírus SARS-CoV-2, pertence à família dos betacoronavírus, e seus sintomas são semelhantes aos da gripe causada pelo vírus influenza, com o pulmão sendo o principal órgão afetado. Objetivo: Realizar uma revisão da literatura sobre a fisiopatologia da COVID-19, suas repercussões e sequelas no sistema nervoso. Fonte de dados: A pesquisa foi realizada nas bases de dados PubMed, ScienceDirect, Scielo e Web of Science entre julho e outubro de 2020. As palavras-chave utilizadas foram: "sistema nervoso e COVID-19", "sistema nervoso e COVID-19 e fisiopatologia", "complicações neurológicas e COVID-19", "associações neurológicas e COVID-19". Síntese de dados: Houve o surgimento de sintomas e comprometimento do sistema nervoso em pacientes após a infecção por SARS-CoV-2. Esses sintomas foram comumente divididos em: comprometimento do sistema nervoso central (SNC), do sistema nervoso periférico e da musculatura esquelética. Estudos apontam a cefaleia como a principal manifestação neurológica, assim como o comprometimento do paladar e olfato. Conclusão: Apesar de existirem evidências de neuroinvasão e neurotropismo decorrentes da infecção por SARS-CoV-2, são necessários estudos complementares para uma melhor determinação das manifestações neurológicas centrais e periféricas associadas à COVID-19.
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Revista Brasileira de Pesquisa em Ciências da Saúde - RBPeCS - ISSN: 2446-5577
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