RADIOMORPHOMETRIC INDICES FOR MEASUREMENT OF MINERAL AND BONE DISORDERS IN CHRONIC KIDNEY DISEASE: A LITERATURE REVIEW

Danielly de Fátima Castro Leite, Neli Pieralisi

Resumo


Introduction: the functional deficiency of the kidneys compromises the homeostasis of calcium, phosphorus, vitamin D and parathyroid hormone (PTH), promoting a condition called mineral and bone disorder of chronic kidney disease (BMD-CKD). Radiomorphometric indices such as mandibular cortical index, panoramic mandibular index, mental index, antegonial index, gonial index and trabecular bone pattern were developed to evaluate bone structure. Aim: the objective of the study was to correlate CKD-BMD with radiomorphometric indices, through a literature review. Methods: it was carried out a search in the National Library of Medicine (PubMed) database, using the terms: chronic kidney disease, chronic kidney insufficiency, panoramic radiography, cone-beam computed tomography and radiomorphometric indices, from 2013 to 2024. The articles were selected according to the objective of the proposed review. Results: data from 12 clinical studies that evaluated the correlation between CKD–MBD and radiomorphometric indices. Discussion: according to the studies found, radiomorphometric indices detected bone changes in the mandible and were correlated with secondary hyperparathyroidism due to increased PTH, with increased action of osteoclasts on the bone and release of skeletal calcium, soon resulting in progressive bone loss. Conclusions: radiomorphometric indices can contribute to screening for the detection of bone changes in patients with CKD and clinicians must be vigilant for bony changes on dentomaxillofacial imaging in these patients with CKD.

Palavras-chave


chronic kidney disease-mineral and bone disorder; panoramic radiography; cone-beam computed tomography.

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Referências


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